Category Archives: Publications

NX210c drug candidate peptide strengthens mouse and human blood-brain barriers

Authors: Chris Greene, Nicolas Rebergue, Gwen Fewell, Damir Janigro, Yann Godfrin, Matthew Campbell & Sighild Lemarchant  Source: Fluids and Barriers of the CNS Published online: September 27, 2024. Synopsis: Background: Alterations of blood-brain barrier (BBB) and blood-spinal…

Distinct functional neutrophil phenotypes in sepsis patients correlate with disease severity

Authors: Qingliang Yang, Jordan C. Langston, Roman Prosniak,Samantha Pettigrew, Huaqing Zhao, Edwin Perez, Hannah Edelmann, Nadia Mansoor, Carmen Merali, Salim Merali, Nathaniel Marchetti, Balabhaskar Prabhakarpandian, Mohammad F. Kiani, Laurie E.…

A biomimetic chip to assess subcutaneous bioavailability of monoclonal antibodies in humans

Authors: Vineeth Chandran Suja, Qin M Qi, Kevin Halloran, Jifeng Zhang, Suyog Shaha, Supriya Prakash, Ninad Kumbhojkar, Antoine Deslandes, Sylvain Huille, Yatin R Gokarn, Samir Mitragotri Source: PNAS Nexus Published…

Application of blood brain barrier models in pre-clinical assessment of glioblastoma-targeting CAR-T based immunotherapies

Authors: Jez Huang, Ying Betty Li, Claudie Charlebois, Tina Nguyen, Ziying Liu, Darin Bloemberg, Ahmed Zafer, Ewa Baumann, Caroline Sodja, Sonia Leclerc, Gwen Fewell, Qing Liu, Balabhaskar Prabhakarpandian, Scott McComb,…

3D Tissue and Organ-on-Chip Models

Authors: SynVivo Synopsis: SynVivo® is a cell-based microfluidic platform that provides a morphologically and physiologically realistic microenvironment allowing real-time study of cellular behavior, drug delivery, and drug discovery. SynVivo’s 3D…

A Microfluidic Platform for Cavitation-Enhanced Drug Delivery

Authors: Giulia Grisanti, Davide Caprini, Giorgia Sinibaldi, Chiara Scognamiglio, Giulia Silvani , Giovanna Peruzzi, and Carlo Massimo Casciola Source: MDPI Open Access Journals Micromachines Published online: June 3, 2021. Synopsis:…

A 3-dimensional microfluidic platform for modeling human extravillous trophoblast invasion and toxicological screening

Authors: Yong Pu, Jeremy Gingrich and Almudena Veiga-Lopez Source: pubs.rsc.org Lab on a Chip Received: October 7, 2020. Accepted: November 2, 2020. Published online: November 9, 2020. Synopsis: Placental trophoblast…

Cellular Interactions of Liposomes and PISA Nanoparticles during Human Blood Flow in a Microvascular Network

Authors: Mai N. Vu, Hannah G. Kelly, Adam K. Wheatley, Scott Peng, Emily H. Pilkington, Nicholas A. Veldhuis, Thomas P. Davis, Stephen J. Kent, and Nghia P. Truong Source: onlinelibrary.wiley.com…

Experimental Approaches to Evaluate Leukocyte-Endothelial Cell Interactions in Sepsis and Inflammation

Authors: Kilpatrick, Laurie E.; Kiani, Mohammad F. SHOCK: May 2020 – Volume 53 – Issue 5 – p 585-595 doi: 10.1097/SHK.0000000000001407 Synopsis: Sepsis is a life-threatening syndrome of organ dysfunction…

Neutrophil‐endothelial interactions of murine cells is not a good predictor of their interactions in human cells

Authors: Fariborz Soroush, Yuan Tang, Omar Mustafa, Shuang Sun, Qingliang Yang, Laurie E. Kilpatrick, Mohammad F. Kiani Synopsis: All drugs recently developed in rodent models to treat inflammatory disease have…