Authors: Tori B. Terrell-Hall, Amanda G. Ammer, Jessica I. G. Griffith, and Paul R. Lockman
Source: ncbi.nlm.nih.gov
Fluids Barriers CNS. 2017; 14: 3.
Published online 2017 Jan 23. doi: 10.1186/s12987-017-0050-9
Synopsis: The lack of translatable in vitro blood-tumor barrier (BTB) models creates challenges in the development of drugs to treat tumors of the CNS and our understanding of how the vascular changes at the BBB in the presence of a tumor.