Description
SynVivo is a distributor of Cedarlane Human Cerebral Microvascular Endothelial Cell Line (hCMEC/D3, Cat #CLU512):
The hCMEC/D3 cell line is a stable and easily grown blood-brain-barrier model, derived from cerebral microvessel endothelial cells (CECs) via lentiviral transduction with SV40 T antigen and human telomerase reverse transcriptase (hTERT). These cells exhibit a spindle-shaped, elongated morphology similar to primary brain endothelial cell cultures and demonstrate contact inhibition at confluence when cultured on collagen type I or IV.
The hCMEC/D3 line expresses key brain endothelial markers, adherence junction (AJ) and tight junction (TJ) proteins, as well as functional ABC transporters characteristic of the brain epithelium.
For detailed product information, refer to the product sheet at hCMEC/D3 Cell Line Data Sheet.
